Subsequent studies have supported these findings, also indicating an increasing trend in the proportion of advanced disease among younger patients over decades, along with disproportionately poorer 5-year EAC-free survival and overall survival compared to older cohorts [ 4 , 7 ].
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Characteristics of early- versus late-onset esophageal adenocarcinoma: insights from the National Inpatient Sample 2016-2020.
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