Lard intake results in better hypothalamic leptin responsiveness than beef tallow intake during overnutrition.

PLoS One · 2025 · PMC12279138 · PMID 40690443

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a decreasing trendno p-value reported

Compared with mice fed a normal chow as 10 kcal% fat , lard-fed as 45 kcal% fat mice showed a decreasing trend in leptin sensitivity, whereas beef tallow-fed mice exhibited a significant decrease in leptin sensitivity.

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