Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.

Front Oncol · 2025 · PMC12279481 · PMID 40697374

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hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP ≤ 0.001actually significant

Statistical analysis confirmed that the reduction in cell viability was highly significant across different concentrations and time points (all P ≤ 0.001 ), indicating a robust dose- and time-dependent anti-proliferative effect of ITZ on Ishikawa cells.

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