Temporal trends in ED burden From 1990 to 2021, ASRs of GERD showed an increasing trend [EAPC of ASIR: 0.10 (95% CI: 0.06, 0.13); EAPC of ASDR: 0.08 (95% CI: 0.04, 0.12)] (Fig. 1 and Table 1 ).
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Global burden of esophageal diseases: a comprehensive analysis of disease trends and risk factors from 1990 to 2021.
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