Association between hs-CRP/HDL-C ratio and risk of prediabetes or diabetes: a cross-sectional study based on NHANES 2015-2023.

BMC Endocr Disord · 2025 · PMC12281851 · PMID 40696331

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an increasing trendno p-value reported

An increasing trend in the prevalence of prediabetes and diabetes was observed with rising hs-CRP/HDL-C ratio (28.72–44.10% and 4.38–17.34%, respectively).

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highly significantno p-value reported

In the RCS models, we randomly removed or re-included the above covariates in repeated modeling processes, and found that the nonlinear associations between hs-CRP/HDL-C and both prediabetes and diabetes risks remained highly significant ( P for nonlinearity < 0.001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.