Large-scale global molecular epidemiology of antibiotic resistance determinants in <i>Streptococcus pneumoniae</i>.

This is coupled with an MDR rate of over 24% and an increasing trend in recent years and highlights the necessity for increased surveillance efforts, as an increase in antibiotic usage in both South America and Asia is likely to be seen in upcoming years, together with rapid economic development in parts of these continents [ 38 ].

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