The m6A demethylase FTO regulates TNF-α expression in human macrophages following Toxoplasma gondii infection.

PLoS Negl Trop Dis · 2025 · PMC12282902 · PMID 40663568

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a decreasing trendno p-value reported

gondii infection decreased significantly for TNF-α and IL-1β in the shFTO group compared to the control group, and the secretion of IL-6 in the shFTO group showed a decreasing trend but was not statistically significant ( Fig 6H - 6J ).

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