An increase in the magnesium ion concentration can reduce calcium influx to inhibit apoptosis, reduce ROS formation, induce vasodilation in cochlear arterioles to limit ischemia and decrease the damage of cochlear hair cells.[ 72 ] One study has also found that statins can improve hair cell survival by reducing oxidative stress, dramatically alleviating NIHL.[ 73 ] C ONCLUSION The detrimental effects of noise on auditory perception occur gradually, making early detection and treatment highly significant.
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Drug-Therapeutic Strategies for Noise-Induced Hearing Loss: A Narrative Review.
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