an increasing trendp = 0.06
An increasing trend of Aβ 1–42 /Aβ 1–40 ratio was observed in VGs 0.005 (CI: −0.001, 0.010, p = 0.06) compared to RMEs, however was not statistically significant. p-tau181 Plasma p-tau181 was significantly higher in the LOV group compared to RMEs (p < 0.01) ( Figure 1(b) ). p-tau181 was not found to be statistically significantly different between other PBDs and RME.