Early nanoparticle intervention preserves motor function following cervical spinal cord injury.

This may be significant due to male and female mice exhibiting different immune responses following injury, with male mice exhibiting worse microglia accumulation in the injury and worse neuron sparing as a result. 44 , 45 Our results suggest that even though neuron survival is not dependent upon the time of first NP administration, early administration of NPs may maintain neuronal connections more effectively than later administration.

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