After the second dose, there was a decreasing trend in the correlation strength between FcγR binding levels to OC43 and HKU1 IgG and age (Spearman r range for FcγRIIa, FcγRIIIa, and FcγRIIb: 0.21–0.41; 95% CI range: −0.0090 to 0.58) ( Supplementary Table S6 ).
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Age differences in immunity to human seasonal coronaviruses and the immunogenicity of ChAdOx1 nCoV-19 (AZD1222).
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