Stochastic cell-intrinsic stem cell decisions control colony growth in planarians.

The co-inhibition of the two lineages resulted in a highly significant decrease in colony size ( Figure 4I ) and a significant increase in the failure to establish colonies ( Figure 4J ; 12/23; 52%), compared to their controls (4/18; 22%; Fisher’s exact test two-tailed p=1.8 × 10 –5 ).

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