Compared to the normal group, the gut microbiome diversity showed a decreasing trend in the sleepless group, which is consistent with previous findings that gut microbiome diversity is positively correlated with sleep efficiency and total sleep time ( Smith et al., 2019 ).
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Characteristics and influencing factors of gut microbiota in population with sleep disorders.
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Diversity analysis showed that the Shannon index exhibited an increasing trend in the sleepless group, which contrasted with the changes in gut microbiome diversity ( Figure 4B ).