Validation of High Ischemic and Bleeding Risk Criteria of European Guidelines in Peripheral Arterial Disease.

risk HIR high ischemic risk MACLE major adverse cardiovascular and limb event(s) PAD peripheral arterial disease ROC receiver-operating characteristic Peripheral arterial disease (PAD) is a prevalent condition linked to systemic atherosclerosis, affecting over 200 million individuals globally with an increasing trend. 1 , 2 Patients with PAD are at high ischemic risk (HIR) of serious cardiovascular and limb-related complications, such as myocardial infarction, stroke, acute limb ischemia, major amputations, and mortality. 3 , 4 , 5 On the other hand, the presence of PAD is one of the factors associated with hig

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