Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice.

JCI Insight · 2025 · PMC12288896 · PMID 40459948

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0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

a nonsignificant trendP = 0.1so close (0.05 < p ≤ 0.1)

Comparing Gba1 (L444P+E326K, combined) Plb versus 5b showed a nonsignificant trend in improved GCase maturation ( P = 0.1) (data not shown).

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