Efficacy of Tripterygium glycosides in immune-mediated kidney diseases as a immunomodulation drug in combination with conventional immunosuppressive agents: a systematic review and meta-analysis of randomized controlled trials.

Front Pharmacol · 2025 · PMC12289580 · PMID 40717986

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an increasing trendno p-value reported

Further subgroup analysis revealed that groups with larger sample sizes exhibited an increasing trend in the effect size of BUN improvement, which could be due to various factors, such as more reliable results due to increased statistical power, reduced random error, or a broader representation of patient characteristics, which may lead to a clearer demonstration of the treatment effect.

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a decreasing trendno p-value reported

Further subgroup analysis revealed that the effect size of Cr improvement increased with longer treatment course but showed a decreasing trend with higher TG dosages.

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