Epigenetics and Mitochondrial Biogenesis: The Role of Sirtuins in HIV Neuropathogenesis.

Mol Neurobiol · 2025 · PMC12289736 · PMID 40198445

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a decreasing trendno p-value reported

an increasing trendno p-value reported

In the mitochondrial fractions, HIV infection appeared to regulate NRF-1 and NRF-2 differentially: NRF-1 showed an increasing trend, while NRF-2 exhibited a decreasing trend in PWH brain tissues compared to uninfected controls (Fig. 2 e–f).

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