Cytokines and immune biomarkers in neurodegeneration and cognitive function: A systematic review among individuals of African ancestry.

Alzheimers Dement · 2025 · PMC12290485 · PMID 40709483

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highly significantno p-value reported

Even when p.R47H is excluded, the association of TREM2 variants with AD remains highly significant, suggesting that additional TREM2 variants contribute to AD risk. 35 BDNF, due to its critical role in neuronal development and survival, also offers a key functional candidate gene for AD.

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