Microbial Profile and Antibiotic Resistance Patterns in Bile Aspirates from Patients with Acute Cholangitis: A Multicenter International Study.

Antibiotics (Basel) · 2025 · PMC12291890 · PMID 40723982

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Interestingly, an investigation performed in South Korea identified monomicrobial infections in 98.1% of the AC cases, revealing an increasing trend in the detection of Gram-negative agents, particularly Enterobacterales , and a decreasing trend of Gram-positive agents, namely Enterococci , over time [ 32 ].

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