highly significantp < 0.001
The statistical test (Z = 4.782) confirms a highly significant difference ( p < 0.001*) in miR-155 expression between cancer and normal tissues ( Figure 1 ).
The statistical test (Z = 4.782) confirms a highly significant difference ( p < 0.001*) in miR-155 expression between cancer and normal tissues ( Figure 1 ).
However, there was a trend toward significance for neoadjuvant treatment ( p = 0.059) and response to neoadjuvant therapy ( p = 0.065), with higher mean miR-3173 expression observed in patients who received neoadjuvant treatment and those with response scores of 4-5. miR-3173 expression was also higher in grade III tumors (9.62 ± 7.11) compared to grade II (3.93 ± 4.53) and grade I (1.04) tumors, although this difference was not statistically significant ( p = 0.174).
Although there is a slight trend suggesting that higher expression might be associated with worse survival, this difference was not strong enough to be considered meaningful.