Barely Significant
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On-treatment blood pressure and dose-dependent effects of ARNI in heart failure with reduced ejection fraction: Insights from a multicenter registry.

PLoS One · 2025 · PMC12303280 · PMID 40720474

2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

a decreasing trendp < 0.001actually significant
Factors associated with low-dose ARNI The average ARNI dose demonstrated a decreasing trend associated with lower average on-treatment SBP (r = 0.253, p < 0.001); patients with lower SBP received lower ARNI doses ( S1 Fig ).

also in 24,192 other papers

a slightly increasing trendno p-value reported
In contrast, the low-dose group demonstrated a decreasing trend of the ARNI dose, while the mean SBP showed a slightly increasing trend.

also in 304 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.