Edible Algae Reduce Blood Pressure in Humans: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

J Hum Nutr Diet · 2025 · PMC12304617 · PMID 40726022

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.2160

boldest claim

The sentences

borderline significantp = 0.051so close (0.05 < p ≤ 0.1)

For DBP, the univariable model indicated a borderline significant effect of algae dosage on DBP reduction, with an estimated effect of −0.52 mmHg per g/day (95% CI: −1.04 to 0.00; p = 0.051), with moderate heterogeneity ( I 2 = 58%).

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marginally significantp = 0.063so close (0.05 < p ≤ 0.1)

Algae dosage became marginally significant (−0.35 mmHg per g/day; 95% CI: −0.73 to 0.02; p = 0.063).

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a nonsignificant trendp = 0.216not close (p > 0.1)

In the univariable model (Model 1), algae dosage showed a nonsignificant trend toward SBP reduction, with an estimated effect of −0.49 mmHg per g/day (95% CI: –1.27 to 0.29; p = 0.216), with substantial residual heterogeneity ( I 2 = 67%), suggesting that dosage alone did not account for the variability across studies.

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