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Trends and drivers of blindness and vision loss burden attributable to age-related macular degeneration from 1990 to 2021: findings from the Global Burden of Disease Study 2021.

BMJ Open · 2025 · PMC12306362 · PMID 40701607

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a decreasing trendno p-value reported
Results Age-standardised prevalence and DALY rates of BVL attributable to AMD showed a decreasing trend, with a global net drift in prevalence of −0.35% (95% CI: −0.38 to −0.32) per year.

also in 47,180 other papers

an increasing trendno p-value reported
The high-middle SDI region exhibited an increasing trend in period risk from 1990 to 2021.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.