Finally, the interpretation of the results may be complicated by the fact that values of AA or DHA (and LA or EPA) at T0 are in fact the result of two separate factors: first the (higher or lower) values present before the acute phase of the disease, and second the extent of decrease resulting from the more or less significant use of these substrate for the biosynthesis of pro-inflammatory (in the case of AA and LA) or anti-inflammatory (for DHA and possibly EPA) biologically active metabolites, whose balance may ultimately affect the course of the inflammatory response.
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Exploratory study of the effect of DHA supplementation on blood fatty acids and inflammatory markers in children with MIS-C.
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