marginally significantP = 0.056
Notably, non-responders exhibited significantly higher LRPS expression compared with responders ( Supplementary Figure S5A ; Wilcoxon test, P = 0.015), while CCL20 showed a marginally significant upregulation trend in non-responders ( Supplementary Figure S5B ; Wilcoxon test, P = 0.056). 3.8 CCL20 promotes HCC cell proliferation, migration, invasion, and lactate production in vitro To elucidate the biological functions of CCL20 in HCC, we conducted a series of in vitro experiments using Hep3B and MHCC97H cell lines.