On the basis of the population PK and exposure–response analysis, there was a positive trend for overall response rate (ORR) with increasing teclistamab exposure, with a plateau observed at the RP2D and no exposure–response trend for safety [ 19 ].
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Teclistamab Dosing in Responders: Modeling and Simulation Results from the MajesTEC-1 Study in Relapsed/Refractory Multiple Myeloma.
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