A side-by-side comparison of variant function measurements using deep mutational scanning and base editing.

Nucleic Acids Res · 2025 · PMC12311789 · PMID 40744495

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highly significantno p-value reported

Highly significant domains that have been previously implicated in transformation, such as the CC [ 83 , 84 ], SH2 [ 84–86 ], Kinase [ 87 ], and FAB domains [ 88 , 89 ] show significant depletion.

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