Role of vertebral fat fraction and R2* based on fat analysis and calculation technique in the quantitative assessment of osteoporosis.

BMC Musculoskelet Disord · 2025 · PMC12312511 · PMID 40739620

Europe PMC DOI

hedged sentence

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

borderline significanceP = 0.072so close (0.05 < p ≤ 0.1)

Although R2* lacked independent predictive value for osteopenia and osteoporosis, its borderline significance in the osteopenia group ( P = 0.072) suggests potential clinical relevance as an early-warning biomarker for initial bone loss.

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