Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase.

Nat Commun · 2025 · PMC12313947 · PMID 40745179

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a decreasing trendno p-value reported

In addition, a clear correlation is observed between the node and betweenness centrality distributions in WT and the mutants, quantitatively demonstrating a decreasing trend of similarity between Y435W to Y435A to Y435S (Supplementary Fig. 6 ).

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