Fenbendazole induces pyroptosis in breast cancer cells through HK2/caspase-3/GSDME signaling pathway.

Front Pharmacol · 2025 · PMC12314287 · PMID 40756987

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0.0100

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highly significantP < 0.01actually significant

The results demonstrated that FBZ treatment led to highly significant upregulation of the relative mRNA and protein expression levels of GSDME, caspase - 3, IL - 18, and IL - 1β (P < 0.01).

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