Overweight and POMC methylation: epigenetic associations with adolescent depression.

BMC Psychiatry · 2025 · PMC12315330 · PMID 40745539

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

a marginal trendp = 0.063so close (0.05 < p ≤ 0.1)

ANOVA revealed significant group differences in methylation levels at CpG6 and CpG8 ( p < 0.05), with CpG7 showing a marginal trend ( p = 0.063).

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borderline significanceno p-value reported

Given its borderline significance and genomic proximity to significant sites, CpG7 was retained alongside CpG6 and CpG8 for subsequent analyses.

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