Barely Significant
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Prevalence and Phenotype of Transthyretin Val122Ile Variant in the Hispanic Community Health Study/Study of Latinos.

JACC Adv · 2025 · PMC12318275 · PMID 40714577

Europe PMCDOI
1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

trending toward significanceP = 0.08so close (0.05 < p ≤ 0.1)
The prevalence of Val122Ile variant was <1% across all threshold categories of NA proportion, with an apparent U-shaped association trending toward significance ( P = 0.08) that was observed with NA of 40%-50% having the lowest variant prevalence ( Figure 3C ).

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