Development of a Ferritin-Based Nano-Allergen and Its Immunological Effects in vitro and in vivo.

Int J Nanomedicine · 2025 · PMC12318518 · PMID 40755463

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a decreasing trendno p-value reported

However, following rFtn-Blo t 2 intervention, IL-13 levels were significantly suppressed, and IL-4 expression showed a decreasing trend, suggesting that the nanoallergen may partially mitigate Th2-driven inflammation.

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a possible trendno p-value reported

Conversely, the expression levels of IFN-γ and TGF-β exhibited a moderate but non-significant increase ( P = 0.1347 and P = 0.0711, respectively), indicating a possible trend toward immune modulation.

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