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Effectiveness and safety of pembrolizumab for the treatment of Japanese patients with microsatellite instability-high tumors excluding colorectal cancer: a post-marketing surveillance.

Jpn J Clin Oncol · 2025 · PMC12319222 · PMID 40382714

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a decreasing trendno p-value reported
After starting treatment, the incidence rates (per 100 patient-weeks) of treatment-related AEOSI showed a decreasing trend from 1 to 12 months ( Fig. 4 ).

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