Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.

Compared with the control group ( Figure 3D ), the serum cAMP in the model group showed an increasing trend, but the difference was not statistically significant ( P > 0.05).

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Compared with the model group, the aggressive behavior scores of rats in the aromatic Xiang Shao granule group were significantly lower ( P < 0.05), and all other treatment groups showed a decreasing trend. 3.3 The effect of PLE on the content of E2, FSH, LH, cAMP, cGMP and 5-HT in serum of rats with hot flashes As shown in Figure 3A , compared with the control group, the serum E2 of the model group tended to decrease, but the difference was not statistically significant ( P > 0.05).

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