Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis.

While none of the 1463 Reactome pathways were significantly enriched for DC differential expression (corrected p -value at 0.05), two pathways were significantly enriched for AC (Platelet sensitization by LDL and Response to metal ions), three for TI (Cytoprotection by HMOX1, Haem signalling and Response to metal ions), and one was significant for R (Aflatoxin activation and detoxification), and four narrowly missed statistical significance, including two interferon signalling pathways—gamma and alpha/beta (corrected p -value at 0.059, Supplementary Fig. 7B ).

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