Barely Significant
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Core-shell nanofibers for localized melanoma therapy delivering Pioglitazone nanoemulsions and gemcitabine dual loaded system.

Sci Rep · 2025 · PMC12322006 · PMID 40760166

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practically significantno p-value reported
Although the therapeutic concept relies on established drug combinations, the polymer system and nanoemulsion strategy represent a practically significant incremental advancement in localized melanoma therapy.

also in 1,558 other papers

a slight trendno p-value reported
S-1 NFs had no significant effect on tumor cells, although a slight trend toward decreased viability was observed.

also in 4,078 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.