Barely Significant
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The J-shaped association between the ratio of neutrophil counts to prognostic nutritional index and mortality in ICU patients with sepsis: a retrospective study based on the MIMIC database.

Front Cell Infect Microbiol · 2025 · PMC12322749 · PMID 40766844

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marginal significanceno p-value reported
When categorized, in Model 3, Q2 had an HR of 1.01 (95% CI: 0.77 ~ 1.32, P=0.950), Q3 had an HR of 1.33 (95% CI: 1.05 ~ 1.68, P=0.019), and Q4 had an HR of 1.25 (95% CI: 1.00 ~ 1.57, P=0.055), indicating no statistically significant association for Q2 and marginal significance for Q3 and Q4. 60-day and 90-day ICU Mortality: The results for 60-day and 90-day ICU mortality showed that in Model 3, Q2 had an HR of 0.56 (95% CI: 0.38 ~ 0.82, P=0.003) for 60-day mortality and Q3 had an HR of 0.51 (95% CI: 0.34 ~ 0.76, P<0.001), while Q4 had an HR of 0.66 (95% CI: 0.46 ~ 0.95, P=0.027) for 90-day mortality.

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