There was a slight trend toward lower IRS-2–dependent PI3K activity in male Ldlr –/– Acod1 –/– mice.
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Modulation of the ACOD1/itaconate pathway differentially affects atherosclerosis severity across genetic models and sexes.
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There was a slight trend toward lower IRS-2–dependent PI3K activity in male Ldlr –/– Acod1 –/– mice.