Synergistic effects of combined hypnotic drugs on sleep in mice.

Front Pharmacol · 2025 · PMC12325282 · PMID 40771934

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a decreasing trendno p-value reported

an increasing trendno p-value reported

As shown in Figure 5 , compared to the control group, intravenous administration of DMED and ESZ individually resulted in a decreasing trend in the levels of NE, DA, Ach, Glu, and His in brain tissue, while the levels of 5-HT, 5-HIAA, and GABA showed an increasing trend.

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