Measuring the Associations Between Brain Morphometry and Polygenic Risk Scores for Substance use Disorders in Drug-Naive Adolescents.

Behav Genet · 2025 · PMC12325389 · PMID 40711718

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marginally significantno p-value reported

The SU/SUD PRS showed marginally significant effects (0.2–0.4%) on cortical surface area and nucleus accumbens volume, but overall effect sizes were small.

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