Unveiling histotype-specific biomarkers in ovarian carcinoma using proteomics.

Mol Ther Oncol · 2025 · PMC12328698 · PMID 40778374

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highly significantno p-value reported

In contrast to the GSEA, HGSC and MC shared features, showing highly significant enrichment of negative regulation of peptidase and endopeptidase activity, a process that promotes angiogenesis and metastasis when dysregulated. 38 However, since GOEA does not provide directionality of the enrichment, the two histotypes may display opposite direction of regulation.

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