We recommend setting L to a value at least greater than the number of intermediates that are marginally statistically significant, and | r | to a moderately high value (| r | = 0.5 as this performed well in our simulations and is the default value in native SuSiE algorithm).
← all excerpts
Hierarchical joint analysis of marginal summary statistics-Part II: High-dimensional instrumental analysis of omics data.
1
—
—