The Relationship Between Opioid Dose and Opioid-Induced Constipation in Japanese Patients With Cancer Pain: A Post Hoc Analysis of a Prospective Observational Cohort Study.

Cureus · 2025 · PMC12335711 · PMID 40786256

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a numerical trendno p-value reported

We observed a numerical trend suggesting that the incidence of OIC increased with rising opioid doses.

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