Recombinant human growth hormone and brain neoplasm association: a pharmacovigilance and Mendelian randomization analysis based on US FAERS, Japanese JADER, and Canadian CVARD.

Front Pharmacol · 2025 · PMC12339429 · PMID 40799818

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

The sentences

modestly significantno p-value reported

The convergence of evidence from extensive pharmacovigilance signal detection across multiple international databases and the supportive, albeit modestly significant, causal inference from MR analysis provides a compelling argument for an association between rhGH and brain neoplasm.

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