Trends in Epidemiology, Clinical Characteristics, and Outcomes of Infective Endocarditis: A 16-Year Nationwide Cohort Study in Korea.

1 Although IE is known to be rare, with an incidence of 3–10 per 100,000 people, recent studies in Europe and the USA have reported an increasing trend in IE incidence since the beginning of the 21st century. 2 3 4 Multiple factors have been identified as potential contributors to this increase, including epidemiological changes among IE patients, such as aging and the rise in comorbidities, as well as advancements in diagnosis. 2 3 4 5 6 7 8 9 Th

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