Barely Significant
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The effect of oral melatonin on the quality of life, sleep and blood pressure of hemodialysis patients: a randomized clinical trial.

BMC Nephrol · 2025 · PMC12341247 · PMID 40790573

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may be significantno p-value reported
Given the unregulated nature of melatonin, there may be significant variation of bioavailability depending on the source of the exogenous melatonin and the metabolic rate of the patient of which it is administered [ 6 ].

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