Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan.

Ann Clin Transl Neurol · 2025 · PMC12343320 · PMID 40413732

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hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

trending toward significancep = 0.053so close (0.05 < p ≤ 0.1)

When using MAP as the mediator, the indirect effect of MAP on the relationship between age and WMH load was not significant ( p = 0.562), and the effect of MAP on WMH volume was trending toward significance ( p = 0.053) (Figure 3 ).

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