TNF-i responders were significantly different from both HC (FDR < 0.05) and TNF-i non-responders (FDR < 0.05) in the 1600–1700 cm − 1 and close to significance in 1450–1500 cm − 1 spectral regions.
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Serum metabolomics identifies unique inflammatory signatures to distinguish rheumatoid arthritis responders and non-responders to TNF inhibitor therapy.
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