GPER1 is involved in shaping tumor immune microenvironment and its expression is decreased in NSCLC tumorigenesis.

Sci Rep · 2025 · PMC12343848 · PMID 40796933

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

marginally statistically significantno p-value reported

Our results further indicated GPER1 acted as a protective factor in ESCA, KIRC, UCEC, BRCA and LUAD, but was only marginally statistically significant in BRCA and LUAD; in addition, GPER1 was involved in the modulation of immune microenvironment in NSCLC and its low expression could predict the likelihood that LUSC patients will benefit from treatment with ICIs.

also in 312 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.